Time-resolved contrast function and optical characterization of spatially varying absorptive inclusions at different depths in diffusing media
Year: 2004
Authors: De Nicola S., Esposito R., Lepore M., Indovina P.L.
Autors Affiliation: Istituto di Cibernetica del CNR ‘‘E. Caianiello,’’ compr. A. Olivetti, Via Campi Flegrei 34, 80078 Pozzuoli, Italy;
Dipartimento di Medicina Sperimentale, Seconda Universita` di Napoli, Napoli, Italy;
Dipartimento Scienze Fisiche, Universita` ‘‘Federico II,’’ Napoli, Italy
and Istituto Nazionale di Fisica della Materia, Unita` di Napoli, Napoli, Italy
Abstract: The role of a spatially varying absorptive inhomogeneity located at different depths within a turbid material has been investigated. This inhomogeneity has been characterized by a spatially dependent Gaussian distribution of its absorption coefficient. The present study has been performed calculating the time-resolved contrast function in the framework of the first-order perturbative approach to the diffusion equation for a slab geometry and a coaxial measurement scheme. The model has allowed us to take into account different locations of the inclusion along the source-detector axis. The accuracy of time-resolved contrast predictions has been analyzed through comparisons with results of the finite element method that has been used to numerically solve the diffusion equation. Recovery of the absorption perturbation parameter of the inhomogeneity for different axial positions has also been investigated.
Journal/Review: PHYSICAL REVIEW E
Volume: 69 (3) Pages from: 031901-1 to: 031901-7
KeyWords: biological media; diffusion; scattering; absorption; spectroscopyDOI: 10.1103/PhysRevE.69.031901ImpactFactor: 2.352Citations: 3data from “WEB OF SCIENCE” (of Thomson Reuters) are update at: 2024-11-24References taken from IsiWeb of Knowledge: (subscribers only)
