Hard-magnetic cell microscaffolds from electroless coated 3D printed architectures

Year: 2018

Authors: Bernasconi R., Cuneo F., Carrara E., Chatzipirpiridis G., Hoop M., Chen X.Z., Nelson B.J., Pany S., Credi C., Levi M., Magagnin L.

Autors Affiliation: Politecn Milan, Dipartimento Chim Mat & Ingn Chim Giulio Natta, Via Mancinelli 7, I-20131 Milan, Italy; Swiss Fed Inst Technol, Inst Robot & Intelligent Syst, Multiscale Robot Lab, Tannenstr 3, CH-8092 Zurich, Switzerland; Politecn Milan, Dipartimento Chim Mat & Ingn Chim Giulio Natta, Piazza Leonardo da Vinci 32, I-20133 Milan, Italy.

Abstract: The combination of 3D printing and wet metallization is a promising methodology for the manufacturing of functional microdevices able to carry out biomedical tasks in vivo. Following this approach, prototypical cell scaffolds are successfully manufactured in the present work. Functional layers are sequentially deposited employing electroless metallization on stereolitography 3D printed moveable structures. Final devices are characterized and magnetically actuated in a precise way using a novel rolling motion approach, which allows for a superior control over speed and position. From the living cells compatibility point of view, the scaffolds show good biocompatibility with fibroblasts after the application of a gold layer.

Journal/Review: MATERIALS HORIZONS

Volume: 5 (4)      Pages from: 699  to: 707

More Information: The work described in the text was carried out in the framework of the interdepartmental laboratory MEMS&3D at Politecnico di Milano, Milano, Italy. The authors would like to acknowledge networking support by the COST Action MP1407 (e-MINDS) and the SBFI Cost Project No. C16.0061 under the frame of this COST Action. They would also like to acknowledge the contribution of S. Bernasconi to the realization of some images present in the text.
KeyWords: Artificial Bacterial Flagella; Microrobots; Fabrication; Transportation; Metallization; Micromachines; Nanomotors; Nanorobots; Delivery; Release
DOI: 10.1039/c8mh00206a

ImpactFactor: 14.356
Citations: 38
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